???kuaisusuoyin???- 1.General Information
- 2.Gene Ontology
- 3.KEGG pathways
- 4.Sequence
- 5.Pfam domains
- 6.Database Cross reference
- 7.Reference
- 8.Linked
General Information
| ID | MAPK5_HUMAN |
| Name | MAP kinase-activated protein kinase 5 |
| Synonyms | [MAPK-activated protein kinase 5, MAPKAP kinase 5, p38-regulated/activated protein kinase] |
| Function classification | Enzyme |
| Gene Family | |
| Taxonomy | Homo sapiens |
| Status |
Gene Ontology
| GO:0006468 | protein amino acid phosphorylation | BP |
| GO:0007165 | signal transduction | BP |
| GO:0005737 | cytoplasm | CC |
| GO:0005634 | nucleus | CC |
| GO:0004674 | protein serine/threonine kinase activity | MF |
| GO:0004708 | MAP kinase kinase activity | MF |
| GO:0005524 | ATP binding | MF |
| GO:0005515 | protein binding | MF |
KEGG pathways
| hsa04010 | MAPK signaling pathway - Homo sapiens (human) |
Sequence
Pfam domains
| PF00069 | Protein kinase domain |
Database Cross Reference
| Entrez Gene | MAPKAPK5 |
| Ensembl Gene | ENSG00000089022 |
| GeneCards | GC12P110742 |
| Unigene | Hs.413901 |
| RefSeq | NP_003659.2|!@#|NP_620777.1 |
| PharmGKB | PA30633 |
Reference
| 9628874 | New L., Jiang Y., Zhao M., Liu K., Zhu W., Flood L.J., Kato Y., Parry G.C.N., Han J. | "PRAK, a novel protein kinase regulated by the p38 MAP kinase." | EMBO J. 17:3372-3384(1998). | |
| 15489334 | The MGC Project Team | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." | Genome Res. 14:2121-2127(2004). | |
| 10708586 | Sudo T., Maruyama M., Osada H. | "p62 functions as a p38 MAP kinase regulator." | Biochem. Biophys. Res. Commun. 269:521-525(2000). | |
| 18669648 | Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. | "A quantitative atlas of mitotic phosphorylation." | Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). | |
| 17344846 | Greenman C., Stephens P., Smith R., Dalgliesh G.L., Hunter C., Bignell G., Davies H., Teague J., Butler A., Stevens C., Edkins S., O'Meara S., Vastrik I., Schmidt E.E., Avis T., Barthorpe S., Bhamra G., Buck G., Choudhury B., Clements J., Cole J., Dicks E | "Patterns of somatic mutation in human cancer genomes." | Nature 446:153-158(2007). |
Linked
| ???xiangguanfangji??? | |
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| ???xiangguanzhiwu??? | |
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