???kuaisusuoyin???- 1.General Information
- 2.Gene Ontology
- 3.KEGG pathways
- 4.Sequence
- 5.Pfam domains
- 6.Database Cross reference
- 7.Reference
- 8.Linked
General Information
| ID | CCR3_HUMAN |
| Name | C-C chemokine receptor type 3 |
| Synonyms | [C-C CKR-3, CC-CKR-3, CCR-3, CCR3, CKR3, Eosinophil eotaxin receptor] |
| Function classification | Signal Transducer |
| Gene Family | GPCR, rhodopsin-like superfamily |
| Taxonomy | Homo sapiens |
| Status |
Gene Ontology
| GO:0006968 | cellular defense response | BP |
| GO:0006935 | chemotaxis | BP |
| GO:0007204 | elevation of cytosolic calcium ion concentr... | BP |
| GO:0044419 | interspecies interaction between organisms | BP |
| GO:0007188 | G-protein signaling, coupled to cAMP nucleo... | BP |
| GO:0006954 | inflammatory response | BP |
| GO:0007155 | cell adhesion | BP |
| GO:0005887 | integral to plasma membrane | CC |
| GO:0016493 | C-C chemokine receptor activity | MF |
KEGG pathways
| hsa04060 | Cytokine-cytokine receptor interaction - Homo sapiens (human) |
Sequence
Pfam domains
| PF00001 | 7 transmembrane receptor (rhodopsin family) |
Database Cross Reference
| Entrez Gene | CCR3 |
| Ensembl Gene | ENSG00000183625 |
| GeneCards | GC03P046227 |
| Unigene | Hs.506190 |
| RefSeq | NP_001828.1|!@#|NP_847899.1 |
| PharmGKB | PA26168 |
Reference
| 7622448 | Combadiere C., Ahuja S.K., Murphy P.M. | "Cloning and functional expression of a human eosinophil CC chemokine receptor." | J. Biol. Chem. 270:16491-16494(1995). | |
| 8642344 | Daugherty B.L., Siciliano S.J., Demartino J.A., Malkowitz L., Sirotina A., Springer M.S. | "Cloning, expression, and characterization of the human eosinophil eotaxin receptor." | J. Exp. Med. 183:2349-2354(1996). | |
| 8676064 | Ponath P.D., Qin S., Post T.W., Wang J., Wu L., Gerard N.P., Newman W., Gerard C., Mackay C.R. | "Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils." | J. Exp. Med. 183:2437-2448(1996). | |
| 11196669 | Kato H., Tsuchiya N., Izumi S., Miyamasu M., Nakajima T., Kawasaki H., Hirai K., Tokunaga K. | "New variations of human CC-chemokine receptors CCR3 and CCR4." | Genes Immun. 1:97-104(1999). | |
| 12079287 | Vijh S., Dayhoff D.E., Wang C.E., Imam Z., Ehrenberg P.K., Michael N.L. | "Transcription regulation of human chemokine receptor CCR3: evidence for a rare TATA-less promoter structure conserved between Drosophila and humans." | Genomics 80:86-95(2002). | |
| 15489334 | The MGC Project Team | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." | Genome Res. 14:2121-2127(2004). | |
| 9789057 | Albini A., Ferrini S., Benelli R., Sforzini S., Giunciuglio D., Aluigi M.G., Proudfoot A.E.I., Alouani S., Wells T.N.C., Mariani G., Rabin R.L., Farber J.M., Noonan D.M. | "HIV-1 Tat protein mimicry of chemokines." | Proc. Natl. Acad. Sci. U.S.A. 95:13153-13158(1998). |
Linked
| ???xiangguanfangji??? | |
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| ???xiangguanzhiwu??? | |
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| ???xiangguanhuahewu??? | |
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