???kuaisusuoyin???- 1.General Information
- 2.Gene Ontology
- 3.KEGG pathways
- 4.Sequence
- 5.Pfam domains
- 6.Database Cross reference
- 7.Reference
- 8.Linked
General Information
| ID | IBP2_HUMAN |
| Name | Insulin-like growth factor-binding protein 2 |
| Synonyms | [IGF-binding protein 2, IGFBP-2, IBP-2] |
| Function classification | |
| Gene Family | Insulin-like growth factor binding protein |
| Taxonomy | Homo sapiens |
| Status |
Gene Ontology
| GO:0001558 | regulation of cell growth | BP |
| GO:0005520 | insulin-like growth factor binding | MF |
KEGG pathways
Sequence
Pfam domains
| PF00219 | Insulin-like growth factor binding protein |
Database Cross Reference
| Entrez Gene | IGFBP2 |
| Ensembl Gene | ENSG00000115457 |
| GeneCards | GC02P217206 |
| Unigene | Hs.438102 |
| RefSeq | NP_000588.2 |
| PharmGKB | PA29704 |
Reference
| 2479552 | Binkert C., Landwehr J., Mary J.L., Schwander J., Heinrich G. | "Cloning, sequence analysis and expression of a cDNA encoding a novel insulin-like growth factor binding protein (IGFBP-2)." | EMBO J. 8:2497-2502(1989). | |
| 1697583 | Zapf J., Kiefer M., Merryweather J., Musiarz F., Bauer D., Born W., Fischer J.A., Froesch E.R. | "Isolation from adult human serum of four insulin-like growth factor (IGF) binding proteins and molecular cloning of one of them that is increased by IGF I administration and in extrapancreatic tumor hypoglycemia." | J. Biol. Chem. 265:14892-14898(1990). | |
| 1712312 | Agarwal N., Hsieh C.L., Sills D., Swaroop M., Desai B., Francke U., Swaroop A. | "Sequence analysis, expression and chromosomal localization of a gene, isolated from a subtracted human retina cDNA library, that encodes an insulin-like growth factor binding protein (IGFBP2)." | Exp. Eye Res. 52:549-561(1991). | |
| 1710112 | Ehrenborg E., Vilhelmsdotter S., Bajalica S., Larsson C., Sterm I., Koch J., Brondum-Nielsen K., Luthman H. | "Structure and localization of the human insulin-like growth factor- binding protein 2 gene." | Biochem. Biophys. Res. Commun. 176:1250-1255(1991). | |
| 1376411 | Binkert C., Margot J.B., Landwehr J., Heinrich G., Schwander J. | "Structure of the human insulin-like growth factor binding protein-2 gene." | Mol. Endocrinol. 6:826-836(1992). | |
| 15489334 | The MGC Project Team | "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." | Genome Res. 14:2121-2127(2004). | |
| 1726837 | Roghani M., Segovia B., Whitechurch O., Binoux M. | "Purification from human cerebrospinal fluid of insulin-like growth factor binding proteins (IGFBPs). Isolation of IGFBP-2, an altered form of IGFBP-3 and a new IGFBP species." | Growth Regul. 1:125-130(1991). | |
| 17020769 | Kuang Z., Yao S., Keizer D.W., Wang C.C., Bach L.A., Forbes B.E., Wallace J.C., Norton R.S. | "Structure, dynamics and heparin binding of the C-terminal domain of insulin-like growth factor-binding protein-2 (IGFBP-2)." | J. Mol. Biol. 364:690-704(2006). |
Linked
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