靶标详情

快速索引

1.General Information
2.Gene Ontology
3.KEGG pathways
4.Sequence
5.Pfam domains
6.Database Cross reference
7.Reference
8.Linked

General Information

ID	RL3R1_HUMAN
Name	Relaxin-3 receptor 1
Synonyms	[RLN3 receptor 1, Relaxin family peptide receptor 3, Somatostatin- and angiotensin-like peptide receptor, G protein-coupled receptor SALPR, GPCR135]
Function classification	Signal Transducer
Gene Family	GPCR, rhodopsin-like superfamily
Taxonomy	Homo sapiens
Status

Gene Ontology

GO:0005887	integral to plasma membrane	CC
GO:0004982	N-formyl peptide receptor activity	MF

KEGG pathways

Sequence

MQMADAATIATMNKAAGGDKLAELFSLVPDLLEAANTSGNASLQLPDLWWELGLELPDGAPPGHPPGSGGAESADTEARVRILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKL

Pfam domains

PF00001

7 transmembrane receptor (rhodopsin family)

Database Cross Reference

Entrez Gene	RXFP3
Ensembl Gene	ENSG00000182631
GeneCards	GC05P033974
Unigene	Hs.170146
RefSeq	NP_057652.1
PharmGKB

Reference

10806363	Matsumoto M., Kamohara M., Sugimoto T., Hidaka K., Takasaki J., Saito T., Okada M., Yamaguchi T., Furuichi K.	"The novel G-protein coupled receptor SALPR shares sequence similarity with somatostatin and angiotensin receptors."	Gene 248:183-189(2000).
14522968	Liu C., Eriste E., Sutton S., Chen J., Roland B., Kuei C., Farmer N., Joernvall H., Sillard R., Lovenberg T.W.	"Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein coupled receptor GPCR135."	J. Biol. Chem. 278:50754-50764(2003).
15489334	The MGC Project Team	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."	Genome Res. 14:2121-2127(2004).

Linked