靶标详情

快速索引

1.General Information
2.Gene Ontology
3.KEGG pathways
4.Sequence
5.Pfam domains
6.Database Cross reference
7.Reference
8.Linked

General Information

ID	GTR5_HUMAN
Name	Solute carrier family 2, facilitated glucose transporter member 5
Synonyms	[Glucose transporter type 5, small intestine, GLUT-5, Fructose transporter]
Function classification	Transporter
Gene Family
Taxonomy	Homo sapiens
Status

Gene Ontology

GO:0015758	glucose transport	BP
GO:0005975	carbohydrate metabolic process	BP
GO:0015755	fructose transport	BP
GO:0055085	transmembrane transport	BP
GO:0016021	integral to membrane	CC
GO:0005886	plasma membrane	CC
GO:0005355	glucose transmembrane transporter activity	MF
GO:0005351	sugar	MF
GO:0005353	fructose transmembrane transporter activity	MF

KEGG pathways

Sequence

MEQQDQSMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIRQEDE

Pfam domains

PF00083

Sugar (and other) transporter

Database Cross Reference

Entrez Gene	SLC2A5
Ensembl Gene	ENSG00000142583
GeneCards	GC01M009031
Unigene	Hs.530003
RefSeq	NP_003030.1
PharmGKB	PA35880

Reference

1695905	Kayano T., Burant C.F., Fukumoto H., Gould G.W., Fan Y.-S., Eddy R.L., Byers M.G., Shows T.B., Seino S., Bell G.I.	"Human facilitative glucose transporters. Isolation, functional characterization, and gene localization of cDNAs encoding an isoform (GLUT5) expressed in small intestine, kidney, muscle, and adipose tissue and an unusual glucose transporter pseudogene-lik	J. Biol. Chem. 265:13276-13282(1990).
8037665	Mahraoui L., Takeda J., Mesonero J., Chantret I., Dussaulx E., Bell G.I., Brot-Laroche E.	"Regulation of expression of the human fructose transporter (GLUT5) by cyclic AMP."	Biochem. J. 301:169-175(1994).
14702039	Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y	"Complete sequencing and characterization of 21,243 full-length human cDNAs."	Nat. Genet. 36:40-45(2004).
16710414	Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C., H	"The DNA sequence and biological annotation of human chromosome 1."	Nature 441:315-321(2006).
15489334	The MGC Project Team	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."	Genome Res. 14:2121-2127(2004).
11840567	Harris R.A., Yang A., Stein R.C., Lucy K., Brusten L., Herath A., Parekh R., Waterfield M.D., O'Hare M.J., Neville M.A., Page M.J., Zvelebil M.J.	"Cluster analysis of an extensive human breast cancer cell line protein expression map database."	Proteomics 2:212-223(2002).

Linked